Ramon
Estruch

Ramon Estruch

Ramon Estruch

España - Barcelona

Biografía

El profesor Ramón Estruch es un reconocido experto en el campo de la medicina interna. Actualmente, es Consultor Senior del Departamento de Medicina Interna del Hospital Clínic en Barcelona, España. Además, ocupa el cargo de Catedrático de Medicina en la Facultad de Medicina de la Universidad de Barcelona.

El profesor Estruch también es Miembro del Comité Directivo del CIBER de Obesidad y Nutrición del Instituto de Salud Carlos III, que forma parte del Gobierno de España. Asimismo, ejerce como Director Científico de la Fundación Dieta Mediterránea, con sede en Barcelona, España.

Su impresionante trayectoria en investigación se refleja en la publicación de más de 650 artículos en revistas de alto impacto, entre las que se incluyen 'The New England Journal of Medicine', 'JAMA', 'The Lancet', 'Annals of Internal Medicine', 'Archives of Internal Medicine', 'Circulation' y 'American Journal of Nutrition', entre otras destacadas publicaciones científicas.

Es importante resaltar los resultados del estudio "Efectos de la Dieta Mediterránea en la prevención primaria de la enfermedad cardiovascular" (estudio PREDIMED), el cual fue publicado en 'The New England Journal of Medicine' y se convirtió en el segundo artículo original más leído en el año 2013. Este estudio ha sido fundamental en la elaboración de guías dietéticas recomendadas por diversos gobiernos y sociedades científicas alrededor del mundo.

Por último, es relevante mencionar que el profesor Ramón Estruch ha sido reconocido como 'Highly Cited Researcher' por Claryvate Analytics, USA, durante los años 2018, 2019, 2020 y 2021.

Filiaciones

- Departamento de Medicina Interna del Hospital Clínic (Barcelona, España)
- Facultad de Medicina de la Universidad de Barcelona
- CIBER
- Fundación Dieta Mediterránea
- FIVIN

Áreas de especialización

- Medicina interna
- Alimentación
- Dieta mediterránea

Abstract

2023 Conferencia en memoria de Serge Renaud: Patrón de consumo, dieta y cáncer

Drinking patterns, dietary habits, and cancer

The consumption of fermented foods as wine is as old as mankind. If its consumption has been maintained for so long, it must be because these foods have healthy properties.

Over 100 observational studies have reported a lower risk of overall mortality, cardiovascular mortality, myocardial infarction, cardiovascular events, and type 2 diabetes in moderate alcohol drinkers compared to abstainers or heavy drinkers. Thus, there is a large consensus on the cardioprotective effects of moderate consumption of alcoholic beverages, especially wine. However, some recent publications have questioned the recommendations of several guidelines and concluded that there is no threshold in the relationship between alcohol consumption and incidence of cancer, underlying that the risk of all-cause mortality and incidence of cancer (especially breast cancer) rises with increasing alcohol consumption and that the level that minimizes health loss is zero. Thus, despite that long relationship with alcoholic beverages, epidemiology and nutrition experts still debate on the overall health effects of chronic alcohol consumption.

Alcohol misuse is considered as the third largest contributor to all cancer cases among women. Most part of the higher cancer incidence is attributable to high ethanol intake, but moderate alcohol consumption (5-14.9 g/d) was associated with an increased risk of overall breast cancer in a prospective large cohort study of female nurses. By contrast, in a deep analysis of the women included in the PREDIMED trial, those who were moderate or light alcohol drinkers had incidence rates of invasive breast cancer that were significantly lower than those of abstainers. When comparing the effects of different alcohol beverages, women who reported to usually drink red wine and follow-up a traditional Mediterranean diet had a nearly 80% reduced incidence of breast cancer.

In conclusion, despite the well-known carcinogenic effect of alcohol (ethanol), moderate alcohol consumption, mainly as red wine, in the setting of a healthy dietary pattern such as the Mediterranean diet is associated with a reduced incidence of breast cancer in postmenopausal women. This protective effect should be attributed to the polyphenol content of alcoholic beverages, especially red wine.

Acknowledgments: The author is grateful to the CIBEROBN from the Instituto de Salud Carlos III (ISCIII), Madrid, Spain, and the Generalitat de Catalunya (2021SGR 01194). INSA-UB is a Maria de Maeztu Unit of Excellence (grant CEX2021-001234-M funded by MICIN/AEI/FEDER, UE).